Macherey-Nagel GmbH
NUCLEOSIL® standard silica phases for HPLC
NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure. Wide acceptance as routine packings for very different fields of chromatography.
One of the first spherical silicas used in HPLC Developed in the early seventies, it became a world-renowned HPLC packing Still found in many analytical and preparative applications An absolutely reliable choice in HPLC The largest variety of modified HPLC silicas available on the market |
 |
| Phase |
Modification |
Formula |
| RP phases |
| NUCLEOSIL® C18 |
medium density octadecyl, endcapped |
-(CH2)17-CH3
|
| NUCLEOSIL® C18 AB |
crosslinked octadecyl, endcapped, high steric selectivity |
-(CH2)17-CH3
|
| NUCLEOSIL® C18 HD |
high density octadecyl, endcapped |
-(CH2)17-CH3
|
| NUCLEOSIL® C18 Nautilus |
hydrophilic octadecyl, embedded polar group, endcapped |
-(CH2)17-CH3
|
| NUCLEOSIL® Protect I |
special RP phase with protective polar group, endcapped |
|
| NUCLEOSIL® C8 ec |
medium density octyl, endcapped |
-(CH2)7-CH3
|
| NUCLEOSIL® C8
|
standard octyl, not endcapped |
-(CH2)7-CH3
|
| NUCLEOSIL® C8 HD |
high density octyl, endcapped |
-(CH2)7-CH3
|
| NUCLEOSIL® C4
|
medium density butyl, endcapped |
-(CH2)3-CH3
|
| NUCLEOSIL® C2
|
dimethyl |
-(CH3)2
|
| NUCLEOSIL® C6H5
|
standard phenyl, not endcapped |
-(CH2)3-C6H5
|
| Polar phases |
| NUCLEOSIL® CN |
cyanopropyl (nitrile) |
-(CH2)3-CN |
| NUCLEOSIL® OH |
diol (dihydroxypropyl) |
-(CH2)3-O-CH2-CH(OH)-CH2OH |
| NUCLEOSIL® NH2
|
aminopropyl |
-(CH2)3-NH2
|
| NUCLEOSIL® N(CH3)2
|
dimethylamino |
-(CH2)3-N(CH3)2
|
| NUCLEOSIL® SA |
benzenesulfonic acid, strongly acidic cation exchanger (SCX) |
-(CH2)3-C6H4-SO3Na |
| NUCLEOSIL® SB |
quaternary ammonium groups, strongly basic anion exchanger (SAX) |
-(CH2)3-C6H4-CH2-N+(CH3)3Cl–
|
| |
|
|
| NUCLEOSIL® SiOH |
unmodified |
(SiO2)n
|
Summary of available NUCLEOSIL® phases
