Regis Technologies
GC Derivatization Reagents
Derivatization is primarily performed to modify an analyte's functionality to enable chromatographic separations. For more than 30 years, Regis has been a leader in the manufacture of highly pure derivatization reagents for gas chromatography. The formation of chemical derivatives to facilitate meaningful analysis has long been a common practice in gas chromatography. For the analytical chemist, judicious use of derivatization can be the key to unlocking and simplifying a great many complex and perplexing separation problems. Derivatization, accomplished through alteration of functional groups, provides:
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Increased sample volatility
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Improved selectivity and chromatographic efficiency
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Enhanced detectability
GC Derivatization Reagents | Applications / Technical Information | Literatur |
Acylation Reagents | Derivatization Methods/Functional Groups Charts | Review of GC Derivatization Methods |
Alkylation Reagents | GC/MS Melamine Testing Method | Derivatization Prodedures |
GC Chiral Derivatization | GC Derivatization Brochure | |
Silylation Reagents | Hydrox-Sil Concentrate |
Sample volatility or thermal stability is crucial in GC applications. If a sample does not possess these important characteristics, GC analysis is highly unproductive. Derivatization techniques have been developed to address these issues to insure successful separations. In GC Derivatization, replacement of active hydrogen in functional groups, such as -COOH, -OH, -NH, and -SH, is the primary area of concern and is accomplished through silylation, acylation or alkylation.