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  • Fresh of the Press News
  • Highlighted Products
  • Bibliography
  • Chromatography
  • Clinical Controls and HPLC Kits
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  • Spare Parts HPLC Instruments
  • Suppliers
  • Vials and Caps
  • Terms and conditions
  • Starpure Catalogue 2024

Regis Technologies

Ion Pair Reagents

Ultra pure Ion pair reagents and buffers



Figure 1
When used with common hydrophobic HPLC phases in the reversed-phase mode, ion pair reagents can be used to selectively increase the retention of charged analytes (Figure 2).
 
For in-depth information, see:
  • Ion Pair Details
  • Ion Pair Method Development

Regis manufactures both ultrapure anionic Sulfonate (S-series) and cationic Quaternary Amine (Q-Series) ion pair concentrates in the following alkyl chain Iengths: pentyl, hexyl, heptyl, octyl, and dodecyl. Alkyl chains are represented by cardinal numbers in the naming of our products, i.e., 5, 6, 7, 8, and 12.

Although ion exchange chromatography has become a popular mode of separation, it is not useful in aIl situations. The advantages of ion pair chromatography over ion exchange chromatography are:

  • Simple preparation of buffers Wide choice of carbon chain Iengths for improved retention and separation
  • Signiscantly reduced separation time
  • Simultaneous separation of both ionized and nonionized solutes
  • Highly reproducible results Improved peak shape

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