ChiroSil® Crown-Ether Chiral Columns
For Amino Acids and Compounds with Primary Amines
The ChiroSil® (RCA)(+) and (SCA)(-) chiral stationary phases (CSPs) were developed by RStech Corporation in Daejeon, South Korea. The ChiroSil Chiral Stationary Phases are prepared by a covalent trifunctional bonding of (+) or (-) - (18-Crown-6)-tetracarboxylic acid as the chiral selector. This chiral stationary phases is the choice for the separation of amino acids and compounds containing primary amines on the analytical or preparative scale.
Covalent phase bonding of ChiroSil columns are long-lasting, unlike their coated preparative column counterparts where non-covalent coatings can leach off.
Covalent bonding enables their use as preparative columns.
Columns have capacity to tolerate sample overload.
Ability to Invert Elution Order
By using ChiroSil CSPs in the opposite absolute configuration, you can invert the elution order so that trace enantiomers elute before the major ones. This feature is extremely desirable for enantiomeric purity determinations.
Universal Solvent Compatibility
The covalent bonding ensures universal solvent compatibility and allows operation under ambient conditions