Regis Technologies
Chiral Chromatography
Whelk-O® 1
Analytical to Preparative Columns
The Whelk-O 1 is useful for the separation of underivatized enantiomers in a number of families including amides, epoxides, esters, ureas, carbamates, ethers, aziridines, phosphonates, aldehydes, ketones, carboxylic acids, alcohols and non-steroidal anti-inflammatory drugs (NSAIDs). This π-electron acceptor/π-electron donor phase exhibits an extraordinary degree of generality. The broad versatility observed on the Whelk-O 1 column compares favorably with polysaccharidederived chiral stationary phases.
The Whelk-O 1 is useful for the separation of underivatized enantiomers in a number of families including amides, epoxides, esters, ureas, carbamates, ethers, aziridines, phosphonates, aldehydes, ketones, carboxylic acids, alcohols and non-steroidal anti-inflammatory drugs (NSAIDs). This π-electron acceptor/π-electron donor phase exhibits an extraordinary degree of generality. The broad versatility observed on the Whelk-O 1 column compares favorably with polysaccharidederived chiral stationary phases.
In addition, because Whelk-O 1 is covalently bonded to the support, the phase is compatible with all commonly used mobile phases, including aqueous systems — a distinct advantage over polysaccharide derived chiral stationary phases. Other advantages include column durability, excellent efficiency, ability to invert elution order and excellent preparative capacity.
| Product | Particle size | Dimension | Code |
| Spherical Silica | |||
| (S,S)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 4.6 mm i.d. | 786101 |
| (S,S)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 10.0 mm i.d. | 786102 |
| (S,S)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 30.0 mm i.d. | 786105 |
| (R,R)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 4.6 mm i.d. | 786201 |
| (R,R)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 10.0 mm i.d. | 786202 |
| (R,R)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 30.0 mm i.d. | 786205 |
| Spherical Kromasil® Silica | |||
| (S,S)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 4.6 mm i.d. | 780101 |
| (S,S)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 10.0 mm i.d. | 780102 |
| (S,S)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 30.0 mm i.d. | 780103 |
| (S,S)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 50.0 mm i.d. | 780104 |
| (R,R)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 4.6 mm i.d. | 780201 |
| (R,R)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 10.0 mm i.d. | 780202 |
| (R,R)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 30.0 mm i.d. | 780203 |
| (R,R)-Whelk-O 1 | 5 µm, 100Å | 25 cm x 50.0 mm i.d. | 780204 |
| (R,R)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 4.6 mm i.d. | 786515 |
| (R,R)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 10.0 mm i.d. | 786525 |
| (R,R)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 21.1 mm i.d. | 786535 |
| (R,R)-Whelk-O 1 | 10 µm, 100Å | 50 cm x 21.1 mm i.d. | 786545 |
| (S,S)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 4.6 mm i.d. | 786615 |
| (S,S)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 10.0 mm i.d. | 786625 |
| (S,S)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 21.1 mm i.d. | 786635 |
| (S,S)-Whelk-O 1 | 10 µm, 100Å | 50 cm x 21.1 mm i.d. | 786645 |
| (S,S)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 30.0 mm i.d. | 786702 |
| (S,S)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 50.0 mm i.d. | 786703 |
| (S,S)-Whelk-O 1 | 10 µm, 100Å | 50 cm x 50.0 mm i.d. | 786704 |
| (R,R)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 30.0 mm i.d. | 786708 |
| (R,R)-Whelk-O 1 | 10 µm, 100Å | 25 cm x 50.0 mm i.d. | 786709 |
| (R,R)-Whelk-O 1 | 10 µm, 100Å | 50 cm x 50.0 mm i.d. | 786710 |
| (R,R)-Whelk-O 1 | 10 µm, 100Å | 50 cm x 30.0 mm i.d. | 786713 |
| (S,S)-Whelk-O 1 | 10 µm, 100Å | 50 cm x 30.0 mm i.d. | 786716 |