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  • Home
  • Fresh of the Press News
  • Highlighted Products
  • Bibliography
  • Chromatography
  • Clinical Controls and HPLC Kits
  • Microdialysis
  • Sample Preparation Products
  • Spare Parts HPLC Instruments
  • Suppliers
  • Vials and Caps
  • Terms and conditions
  • Starpure Catalogue 2024

Macherey-Nagel GmbH

Flash Chromatography

 
Flash chromatography is an established and proven method for (semi)preparative separations since decades, particularly used in synthesis laboratories. Increasing sample quantities and the resulting demand for a high sample throughput caused developments of automated flash chromatography systems.

As an experienced silica manufacturer, MACHEREY-NAGEL offers flash cartridges for the common systems.

Flash chromatography
Flash chromatography is a fast separation method of column chromatography for the purification of organic compounds of preparative scale. The standard method was developed from Still et al. in 1978 [W.C. Still, M. Kahn and A. Mitra, J. Org. Chem 43 (1978) 2913]. Non-automated systems consist of a glass column and a reservoir for the eluent. In flash chromatography, the eluent is pressed with a small excess pressure (1.5–2.0 bar) through a silica bed, manually packed before.

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