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  • Starpure Catalogue 2024

Regis Technologies

Chiral Chromatography

α-Burke 2

 
Analytical to Preparative Columns 
The α-Burke 2 phase is derived from dimethyl N-3,5-dinitro-benzoyl--amino-2,2-dimethyl- 4-pentenyl phosphonate covalently bound to 5 µm silica. This π-acceptor chiral stationary phase is particularly valuable in the HPLC separation of β-blocker enantiomers, an important class of cardiovascular drugs whose enantiomers often exhibit differing pharmacological activities. The α-Burke 2 has been specifically designed to separate the enantiomers of β-blockers without chemical derivatization. In addition, it also resolves the enantiomers of many compounds separated on π-acceptor Pirkle type chiral stationary phases.
 
Product Particle size Dimension Code
Spherical Silica
(R)-Þ-Burke 2 5 µm, 100 Å 25 cm x 10.0 mm i.d. 735235
(R)-Þ-Burke 2 5 µm, 100 Å 25 cm x 21.1 mm i.d. 735236
(R)-Þ-Burke 2 5 µm, 100 Å 25 cm x 4.6 mm i.d. 735035
(S)-Þ-Burke 2 5 µm, 100 Å 25 cm x 10.0 mm i.d. 735237
(S)-Þ-Burke 2 5 µm, 100 Å 25 cm x 21.1 mm i.d. 735238
(S)-Þ-Burke 2 5 µm, 100 Å 25 cm x 4.6 mm i.d. 735037
 
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